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Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer

✍ Scribed by Shibin Zhou; Leigh Zawel; Christoph Lengauer; Kenneth W. Kinzler; Bert Vogelstein


Book ID
117736098
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
196 KB
Volume
2
Category
Article
ISSN
1097-2765

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## Abstract Cellular mechanisms causing cardiac hypertrophy are currently under intense investigation. We report a novel finding in the TGFβ inducible early gene (TIEG) null mouse implicating TIEG1 in cardiac hypertrophy. The TIEG^−/−^ knock‐out mouse was studied. Male mice age 4–16 months were cha