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Characterization of histamine H3receptors in mouse brain using the H3antagonist [125I]iodophenpropit

✍ Scribed by Frank P. Jansen, Takatoshi Mochizuki, Kazutaka Maeyama, Rob Leurs, Hendrik Timmerman


Book ID
118780701
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
654 KB
Volume
362
Category
Article
ISSN
0028-1298

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## Abstract The synthesis of the first high specific activity {^125^I} labelled selective H~3~ antagonist, Iodophenpropit‐ i.e., S‐[3‐(4(5)‐imidazolyl)propyl],N‐[2‐(4‐{^125^I}‐iodophenyl)ethyl]isothiourea sulfate is reported. The radiolabelled compound was prepared by Cu(I)assisted nucleophilic no