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Characterization of histamine H3-receptors in mouse brain using the H3-antagonist [125I]-iodophenpropit

✍ Scribed by JANSEN, F; MOCHIZUKI, T; MACYAMA, K; LEURS, R; TIMMERMAN, H

Book ID: 122611869
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 136 KB
Volume: 31
Category: Article
ISSN: 1043-6618
DOI: 10.1016/1043-6618(95)87343-0

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## Abstract The synthesis of the first high specific activity {^125^I} labelled selective H~3~ antagonist, Iodophenpropit‐ i.e., S‐[3‐(4(5)‐imidazolyl)propyl],N‐[2‐(4‐{^125^I}‐iodophenyl)ethyl]isothiourea sulfate is reported. The radiolabelled compound was prepared by Cu(I)assisted nucleophilic no