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Characterization of heme environment and mechanism of peroxide bond cleavage in human prostacyclin synthase

✍ Scribed by Hui-Chun Yeh; Pei-Yung Hsu; Jinn-Shyan Wang; Ah-Lim Tsai; Lee-Ho Wang


Book ID
116272998
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
538 KB
Volume
1738
Category
Article
ISSN
1388-1981

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## Abstract Citrate synthase (CS), the first and rate‐limiting enzyme of the tricarboxylic acid (TCA) cycle, plays a decisive role in regulating energy generation of mitochondrial respiration. Most mitochondrial proteins are synthesized in the cytoplasm as preproteins with an amino (N)‐terminal mit