Dysfunction of serotonin systems has been implicated in schizophrenia. In the present study, the human 5-HT 1A receptor gene containing the 5 untranslated region was screened in order to detect genetic variations, through which alteration of protein function or level of expression might contribute t
Characterization of new mutations in the coding sequence and 5'-untranslated region of the human prostacyclin synthase gene (CYP8A1)
β Scribed by Dany Chevalier; Christelle Cauffiez; Claudine Bernard; Jean-Marc Lo-Guidice; Delphine Allorge; Fanny Fazio; Nicolas Ferrari; Christian Libersa; Michel Lhermitte; Jean-Claude D'Halluin; Franck Broly
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 217 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0340-6717
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Dysfunctions in serotonergic pathways may underlie several psychiatric disorders. The reuptake of serotonin (5-HT) from synaptic terminals is mediated by a specific transporter (5-HTT). Genetic variation in the gene coding for the 5-HTT protein might be involved in the predisposition to psychiatric
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