We have examined the synthetic N-oxides of five ethylenediamine-type antihistamines using fast atom bombardment (FAB) mass spectrometry and FAB tandem mass spectrometry (MS/MS). Fragmentation of the protonated molecule in the normal and collisionally activated spectra appeared to be characteristic f
Characterization of glucosamine and N-acetylglucosamine oligomers by fast atom bombardment mass spectrometry
β Scribed by C. Bosso; A. Domard
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 553 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1076-5174
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β¦ Synopsis
The oligomers of N-acetylglucosamine [degree of polymerization (d.p.) 2-61 and of glucosamine (d.p. 3-9) were systematically studied by the fast atom bombardment technique. Positive-and negative-ion detection were used successively in each case. The latter provided more information in respect of the number of fragmentation pathways. In addition to the classical fragmentations usually obtained with other oligosaccharidic chains, new species specific to these two series were observed. They depend mainly on the nature of the substituents located on the C(2) positions of the glucosidic units constituting the chain.
π SIMILAR VOLUMES
Three glutathione conjugates of acetaminophen were characterized by fast atom bombardmentlmass spectrometry (FABlMS) and fast atom bombardmentlmass spectrometryhass spectrometry (FABlMSlMS). The conjugates, 3-(glutathion-S-yl)acetaminophen, 3-(glutathion-S-yl)diacetaminophen and 3-(diglutathion-S-yl