Characterization of p53 gene mutations i
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Hisashi Tanaka; Ichio Shibagaki; Yutaka Shimada; Takashi Wagata; Masayuki Imamur
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Article
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1996
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John Wiley and Sons
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French
โ 557 KB
We screened 29 human esophageal squamous cell carcinoma (ESC) cell lines for mutations of the p53 gene through all coding exons and exon-intron junctions. Mutations were found in 22 cell lines (76%), consisting of 20 single-base substitutions, 2 small deletions and I single-base insertion. Out of 20