Previous in vitro studies in rat microsomal preparations suggested that thalidomide is metabolized by the cytochrome P450 system (CYP). In this study, we examined the extent of thalidomide metabolism by preparations of pooled human microsomes, microsomes containing cloned human CYP isozymes (CYP1A2,
Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes
β Scribed by Daniel Stralka; Henry W. Strobel
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 650 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
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