๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Characterization of CHEK2 mutations in prostate cancer

โœ Scribed by Xianglin Wu; Xiangyang Dong; Wanguo Liu; Junjie Chen


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
218 KB
Volume
27
Category
Article
ISSN
1059-7794

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


CHEK2 mutations and HNPCC-related colore
โœ Janina Suchy; Cezary Cybulski; Dominika Wokoล‚orczyk; Oleg Oszurek; Bohdan Gรณrski ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 128 KB

## Abstract Recently, the 1100delC variant of cell cycle checkpoint kinase 2 (CHEK2) has been reported to confer a colorectal cancer risk in hereditary nonโ€polyposisโ€colorectal cancer (HNPCC) and HNPCCโ€related families in the Netherlands. To investigate whether CHEK2 mutations confer increased canc

Colorectal cancer and the CHEK2 1100delC
โœ Mirjam M. de Jong; Ilja M. Nolte; Gerard J. te Meerman; Winette T. A. van der Gr ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 82 KB

## Abstract The __CHEK2__ 1100delC mutation was recently identified as a lowโ€penetrance breast cancer susceptibility allele. The mutation occurred more frequently in families with clustering of breast and colorectal cancers (CRCs) than in families with clustering of breast cancer only. Hence, the 1

Association of two mutations in the CHEK
โœ Natalia Bogdanova; Natalia Enฮฒen-Dubrowinskaja; Sergei Feshchenko; Gennady I. La ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 148 KB ๐Ÿ‘ 2 views

## Abstract The 1100delC mutation of the cell cycle checkpoint kinase 2 (__CHEK2__) gene confers an increased risk for breast cancer, but the clinical impact of other __CHEK2__ gene variants remains unclear. We determined the frequency of two functionally relevant __CHEK2__ gene mutations, I157T an

Unique substitution of CHEK2 and TP53 mu
โœ Li Zheng; Fengwei Wang; Chiping Qian; Roxann M. Neumann; John C. Cheville; Donal ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 256 KB

## Communicated by Marc S. Greenblatt Genetic defects in CHEK2 and TP53 have been implicated in prostate cancer development. However, the interaction of these two genes in prostate cancer tumorigenesis has not been investigated. We previously described 11 CHEK2 mutations in a group of 84 primary p

Prevalent mutations in prostate cancer
โœ Jin-Tang Dong ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB

## Abstract Quantitative and structural genetic alterations cause the development and progression of prostate cancer. A number of genes have been implicated in prostate cancer by genetic alterations and functional consequences of the genetic alterations. These include the __ELAC2__ (__HPC2__), __MS

BRCA2 mutation in a family with heredita
โœ Henrik Grรถnberg; Anna-Karin ร…hman; Monica Emanuelsson; Anders Bergh; Jan-Erik Da ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 71 KB ๐Ÿ‘ 2 views