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Characterization of brain-infiltrating mononuclear cells during infection with mouse hepatitis virus strain JHM

โœ Scribed by Jo S.P. Williamson; Karin C. Sykes; Stephen A. Stohlman


Book ID
119107785
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
668 KB
Volume
32
Category
Article
ISSN
0165-5728

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The pathogenicity and cell tropism of mouse hepatitis virus (MHV-JHM-strain) in the developing mouse (Balblc) and rat (Wistar and Lewis) brain were analysed. Intracranial infection of Balb/c mice at postnatal day 5 induced a lethal encephalitis in all animals. Of Wistar rats infected at day 2 or 5 a