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B-Cell-Mediated Lysis of Cells Infected with the Neurotropic JHM Strain of Mouse Hepatitis Virus

โœ Scribed by Shawn Morales; Beatriz Parra; Chandran Ramakrishna; Dianna M. Blau; Stephen A. Stohlman

Book ID
112273629
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
165 KB
Volume
286
Category
Article
ISSN
0042-6822

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The pathogenicity and cell tropism of mouse hepatitis virus (MHV-JHM-strain) in the developing mouse (Balblc) and rat (Wistar and Lewis) brain were analysed. Intracranial infection of Balb/c mice at postnatal day 5 induced a lethal encephalitis in all animals. Of Wistar rats infected at day 2 or 5 a