Recent data suggests that induction of prostaglandin endoperoxide H synthase-2 (PGHS-2) is critical for the anabolic response of lamellar bone elicited by mechanical strain in vivo. The aim of the present study was to localise PGHS-1 and PGHS-2 in rat tibiae following four-point bending in vivo. Rig
Characterization of autocrine inducible prostaglandin H synthase-2 (PGHS-2) in human osteosarcoma cells
✍ Scribed by E. Wong; C. DeLuca; C. Boily; S. Charleson; W. Cromlish; D. Denis; S. Kargman; B.P. Kennedy; M. Ouellet; K. Skorey; G.P. O'Neill; P.J. Vickers; D. Riendeau
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1997
- Tongue
- English
- Weight
- 390 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
IL-4 also decreased expression of CD14, which is the LPS-LPS-binding protein (LBP) receptor. Down-regulation of this receptor correlated with decreased expression of PGHS-2 and release of PGEz. MATERIALS AND METHODS ## Reagents Recombinant human IL-1p and recombinant human IL-4 were purchased fr
The tumor promoter phorbol 13-myristate 12-acetate (PMA), the best characterized protein kinase C agonist, frequently regulates gene expression via activation of Fos/Jun (AP-1) complexes. PMA rapidly and transiently induces prostaglandin G/H synthase-2 (PGHS-2) expression in murine osteoblastic MC3T