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Characterization of ATP and P2 agonists binding to the cardiac plasma membrane P1,P4-diadenosine 5′-tetraphosphate receptor

✍ Scribed by Grant E. Blouse; Guang Liu; Richard H. Hilderman


Book ID
117049038
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
306 KB
Volume
1375
Category
Article
ISSN
0005-2736

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Diadenosine 5',5"'-P,,P,-tetraphosphate (Ap,A), a n intracellular regulatory nucleotide, has been found to react with the antitumor drug cw-diamminedichloroplatinum(I1J and its aqua derivative to form a single complex. This complex has been purified by highperformance liquid chromatography and chara