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Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient

✍ Scribed by Kazuya Shinmura; Masaya Suzuki; Hidetaka Yamada; Hong Tao; Masanori Goto; Takaharu Kamo; Kiyoko Nagura; Shinji Kageyama; Motohiro Kato; Seishi Ogawa; Masato Maekawa; Kazuya Takamochi; Kazuya Suzuki; Toshio Nakamura; Haruhiko Sugimura


Book ID
115175988
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
483 KB
Volume
58
Category
Article
ISSN
1320-5463

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Patients with Familial Adenomatous Polyposis (FAP) manifest numerous colorectal adenomas as well as benign and malignant extra-colonic lesions. Adenomatous polyposis coli (APC) gene mutations are the underlying genetic defect in FAP. We analyzed germline D N A of 81 unrelated FAP patients and evalua