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Characterization of acylcarnitines using fast atom bombardment mass spectrometry and gas chromatography/mass spectrometry

✍ Scribed by J. F. Van Bocxlaer; M. Claeys; H. Van Den Heuvel; A. P. De Leenheer


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
802 KB
Volume
30
Category
Article
ISSN
1076-5174

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✦ Synopsis


Mass spectral data are reported for an extended series of synthesized acylcarnitines. Direct mass spectrometry was performed using ionization by fast atom bombardment in combination with high-energy collisional activation and B/E linked scanning. The data show that it is possible to distinguish between isomeric compounds using this technique. Gas chromatographic/mass spectrometric analysis data for acylcarnitines, as their acyloxylactone derivatives, are reported. Both electron impact and chemical ionization modes were used, permitting the unequivocal characterization and identification of the various compounds. In view of the recent marked increase in acylcarnitine profiling activities, the comprehensively reported mass spectrometric and gas chromatographic data may be useful for reference purposes.


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