Characterization of a tissue factor/factor VIIa-dependent model of thrombosis in hypercholesterolemic rabbits
โ Scribed by L. Chi; G. Gibson; Y-W Peng; R. Bousley; D. Brammer; M. Rekhter; J. Chen; R. Leadley
- Book ID
- 109148267
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 172 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1538-7933
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The characteristics of a phospholipid surface are of major importance in the activation of factor X in the presence of tissue factor-factor VIIa (TF-VIIa) complex. A possible tool which provides a measure of the surface corrugation and roughness is the fractal dimension analysis. This paper uses the
The effect of shear stress on the ability of tissue factorfactor VIIa complex to activate factor X in a continuous flow reactor was studied. Tissue factor immobilized in a phospholipid bilayer on the inner surface of a capillary tube was exposed to a perfusate containing factors VIIa and X flowing a