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Characterization of a T-cell clone recognizing idiotypes as tumor-associated antigens

✍ Scribed by Stanley J. Waters; Constantin A. Bona


Book ID
113134035
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
543 KB
Volume
111
Category
Article
ISSN
0008-8749

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## Abstract Cyclin‐A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor‐associated genes potentially are useful targets for cancer immunotherapy. However, high‐avidity cyclin‐specific T cells are cons