Characterization of a mutation in the acetolactate synthase of Bacillus subtilis that causes a cold-sensitive phenotype
β Scribed by Frank Wiegeshoff; Mohamed A. Marahiel
- Book ID
- 109329773
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 106 KB
- Volume
- 272
- Category
- Article
- ISSN
- 0378-1097
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## Abstract A novel metabolic engineering technique involving the redirection ofcellular carbon fluxes was employed to reduce acetate production in an __Escherichia coli__ culture. Metabolic engineering was achieved by cloning __E. coli__ the gene for the __Bacillus subtilis__ acetolactate synthase
## Abstract ## Objective Familial cold urticaria (FCU) and MuckleβWells syndrome (MWS) are dominantly inherited autoinflammatory disorders that cause rashes, fever, arthralgia, and in some subjects, AA amyloidosis, and have been mapped to chromosome 1q44. Sensorineural deafness in MWS, and provoca