Characterization of a large chromosomal deletion in the PROS1 gene of a patient with protein S deficiency type I using long PCR
โ Scribed by Zandra R. Holmes; Rogier M. Bertina; Pieter H. Reitsma
- Book ID
- 114425003
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 781 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0007-1048
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DNA sequence analysis of the protein S gene (PROS1) in 22 Spanish probands with type I or III PS deficiency, has allowed the identification of 10 different mutations and 2 new sequence variants in 15 probands. Nine of the mutations, 8 of which are novel, cosegregate with type I or quantitative PS de
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