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Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

✍ Scribed by Willie Wilson III; Fernando Pardo-Manuel de Villena; Beverly D. Lyn-Cook; Pradeep K. Chatterjee; Timothy A. Bell; David A. Detwiler; Rodney C. Gilmore; Isis C. Valladeras; Camille C. Wright; David W. Threadgill; Delores J. Grant

Book ID
116981292
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
524 KB
Volume
84
Category
Article
ISSN
0888-7543

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Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism
✍ Vincent Ménard; Olivier Eap; Mario Harvey; Chantal Guillemette; Éric Lévesque 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 531 KB

UGT2B17 and UGT2B28 are among the most commonly deleted genes in humans and encode members of the uridine diphosphate (UDP)-glucuronosyltransferase 2B (UGT2B) subfamily. They are involved, along with UGT2B15, in the catabolism of sex-steroid hormones. Despite the recent biomedical interest in UGT2B1