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Characterization of a chromosome 8-derived minute marker chromosome using microdissection and FISH in a boy with growth retardation

✍ Scribed by Engelen, J.J.M. ;Schrander-Stumpel, C.T.R.M. ;Theunissen, P.M.V.M. ;Vaes-Peeters, G. ;Albrechts, J.C.M. ;Hamers, A.J.H.


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
127 KB
Volume
118A
Category
Article
ISSN
0148-7299

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Characterization of a supernumerary mark
✍ Kozma, Chahira; Blancato, Jan; Meck, Jeanne; Jiang, Yuan πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 16 KB πŸ‘ 2 views

We describe a 38-year-old adult who has a supernumerary marker chromosome in 40% of metaphase cells which was identified by reverse in situ hybridization with a DNA probe made by microdissection to be derived from chromosome 17. The breakpoints are estimated by G-banding and fluorescence in situ hyb