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Characterization of [3H]YM060, a potent and selective 5-HT3 receptor radioligand, in the cerebral cortex of rats

✍ Scribed by Shinobu Akuzawa; Keiji Miyata; Hisayuki Fukutomi


Book ID
115890257
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
519 KB
Volume
281
Category
Article
ISSN
0014-2999

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Synthesis of [3H]CP-93,129: A selective
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## Abstract The synthesis of [^3^H]‐CP‐93,129, a potent radioligand for the serotonin 5‐HT~1B~ receptor, is described. 5‐Butoxypyrrolo[3,2‐b]pyridine (2) is converted in 3 steps to 5‐butoxy‐1‐phenylsulfonyl‐2‐tritiopyrrolo[3,2‐b]pyridine (3c) via lithiation of C2, iodination of that anion, and trit