Characterization and processing of prostate specific antigen (hK3) and human glandular kallikrein (hK2) secreted by LNCaP cells
✍ Scribed by Väisänen, V; Lövgren, J; Hellman, J; Piironen, T; Lilja, H; Pettersson, K
- Book ID
- 110073099
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 452 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1365-7852
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## Abstract Prostate‐specific antigen (PSA) is a widely used marker for prostate cancer. In the literature, there are reports of nonprostatic expression of PSA that potentially can affect early diagnosis. However, the results are scattered and inconclusive, which motivated us to conduct a more comp
## BACKGROUND. Human prostate-specific antigen (PSA) and human kallikrein 2 (hK2) are expressed primarily by prostate epithelial cells. PSA and hK2 both exist as free protein and complexed with protease inhibitors (e.g., ␣1-antichymotrypsin, ACT) in serum. The expression of PSA and hK2 in LNCaP ce