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Characterization and differential expression of protein kinase C isoforms in PC12 cells Differentiation parallels an increase in PKC beta11

✍ Scribed by Marie W. Wooten; M.Lamar Seibenhener; Yunjo Soh; Sandra J. Ewald; Kimberly R. White; Elizabeth D. Lloyd; Andree Olivier; Peter J. Parker


Book ID
115925727
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
523 KB
Volume
298
Category
Article
ISSN
0014-5793

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The cell line A126-1B2 is a PC12-derived mutant that is resistant to the toxic effects of dibutyryladenosine 3'5'-cyclic monophosphate (dbcAMP) and is deficient in adenosine 3':5'-cyclic monophosphate (CAMP)-dependent protein kinase I1 (PKAII). This mutant formed neurites in response to nerve growth