𝔖 Bobbio Scriptorium
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Characterization and Comparison of Protein Structures. Part II—Comparison

✍ Scribed by V.R. Chechetkin; V.V. Lobzin

Book ID
102610389
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
254 KB
Volume
198
Category
Article
ISSN
0022-5193

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✦ Synopsis

The Fourier methods are applied to the pairwise comparison of C a -backbones in protein structures. The technique allows to assess both the general similarity and the main origins of resemblance (coincident periodicities, similarity of fragments, or large-scale semblance of folding). The analogous methods can be extended to the study of correlations between the structural characteristics for the C a -backbone of one protein and the distribution of physico-chemical parameters along the primary amino acid sequence for the other. Finally, we discuss the problem of clusterization of pairwise data into tree-like hierarchical system.

📜 SIMILAR VOLUMES

Characterization and Comparison of Prote
Characterization and Comparison of Protein Structures. Part I-Characterization
✍ V.R. Chechetkin; V.V. Lobzin 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 310 KB

The quantitative criteria characterizing the regularity of C a -backbones in the protein structures are presented. A technique is based on the Fourier remapping of the Cartesian coordinates for the C a -chain. The Fourier spectra identify the hidden periodicities and symmetries in protein structures