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Characterization and affinity crosslinking of receptors for tumor necrosis factor on human cells

✍ Scribed by Masafumi Tsujimoto; Rena Feinman; Masayoshi Kohase; Jan Vilček

Book ID
115706845
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
821 KB
Volume
249
Category
Article
ISSN
0003-9861

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The expression of specific membrane receptors for TNF-alpha was determined on various human leukemic cell lines differing in their sensitivity to the growth-inhibitory activity of TNF-alpha. Binding studies with '251-labelled TNF-alpha indicated specific binding in 8/10 cell lines with approximately