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Characteristics of the end-joining of DNA double-strand breaks by the ataxia-telangiectasia nuclear extract

✍ Scribed by Akira Tachibana; Masao S Sasaki


Book ID
117052550
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
124 KB
Volume
297
Category
Article
ISSN
0006-291X

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Chromosomal aberrations are believed to result from the incorrect joining of DNA double-strand breaks (DSBs). In an attempt to investigate induction and rejoining quality of DSBs following ionizing radiation exposure in specific genomic locations of mammalian DNA, an experimental approach based on S