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Characteristics of Phorbol Ester- and Agonist-Induced Down-Regulation of Astrocyte Receptors Coupled to Inositol Phospholipid Metabolism

โœ Scribed by Brian Pearce; Christine Morrow; Sean Murphy


Book ID
111174788
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
945 KB
Volume
50
Category
Article
ISSN
0022-3042

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Treatment of murine peritoneal exudate macrophages (PEM) by tumor-prornoting phorbol esters (TPA) results in a rapid loss of binding activity to radioactive-labeled colony-stimulating factor ([1251]-CSF-1) on the cell surface. The inhibitory effect of TPA on PEM i s transient; treated cells recover