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Characteristics of Nucleotide Substitution in the Hepatitis C Virus Genome: Constraints on Sequence Change in Coding Regions at Both Ends of the Genome

✍ Scribed by Smith, Donald B.; Simmonds, Peter

Book ID
113011945
Publisher
Springer
Year
1997
Tongue
English
Weight
641 KB
Volume
45
Category
Article
ISSN
0022-2844

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## Abstract Hepatitis C virus (HCV) infection is characterized by persistence of liver inflammation that often leads to end‐stage liver disease, although the mechanisms are not fully understood. A hyper‐variable region (HVR) has been reported in the E2/NS1 region of the HCV genome, in which strikin