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Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2

✍ Scribed by Jackson, Sarah A.; Davis, Andrew A.; Li, Jun; Yi, Nengjun; McCormick, Shelley R.; Grant, Carly; Fallen, Taya; Crawford, Beth; Loranger, Kate; Litton, Jennifer; Arun, Banu; Vande Wydeven, Kimberly; Sidani, Amer; Farmer, Katie; Sanders, Merideth; Hoskins, Kent; Nussbaum, Robert; Esserman, Laura; Garber, Judy E.; Kaklamani, Virginia G.

Book ID
121686774
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
137 KB
Volume
120
Category
Article
ISSN
0008-543X

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Approximately 2% to 5% of all breast cancers are hereditary, meaning that the cancer predisposition is carried as a monogenic trait. Several highly penetrant breast cancer predisposing genes have been identified. These discoveries will permit a refined description of breast cancer occurring as part