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Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer

✍ Scribed by Schaefer, C; Kim, G G; Albers, A; Hoermann, K; Myers, E N; Whiteside, T L

Book ID: 109998413
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 335 KB
Volume: 92
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6602407

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## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos