One of the earliest responses of quiescent mammalian cells to the addition of serum is an increase in intracellular p H (pH'"). This pH'" change is generally believed to be due to an increased activity of Na'/Hf exchange. A number of investigators have observed steady-state differences in pH'" betwe
Changes of intracellular and externally bound cations accompanying serum stimulation of mouse BALB/c 3T3 cells
โ Scribed by Hisashi Sanui; Harry Rubin
- Book ID
- 115891586
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 959 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
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## Abstract The stimulation of DNA synthesis in quiescent, densityโarrested BALB/cโ3T3 cells by plateletโderived growth factor in plasmaโsupplemented medium was inhibited by the presence of isobutylmethylxanthine (IBMX) and cholera toxin, although neither IBMX or cholera toxin when used alone inhib
## Abstract During the first six passages after their arrival in this laboratory, BALB/c 3T3 mouse cells did not proliferate in serum containingโmedium having an ionic calcium concentration of 0.05 mM or less, but by the ninth passage they had become able to multiply in the presence of these lower