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Changes of enzymic activities in human diploid cell line WI-38 at various passages

โœ Scribed by K.-M. Wang; N.R. Rose; E.A. Bartholomew; M. Balzer; K. Berde; M. Foldvary


Book ID
118875638
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
564 KB
Volume
61
Category
Article
ISSN
0014-4827

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Transcriptional activity of nuclei from
โœ Kiyoshi Nose; Hiroshi Okamoto ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 263 KB

## Abstract Transcriptional activity of nuclei from human diploid fibroblast (WIโ€38) cells at different passage levels was studied with endogenous RNA polymerase. The rate and extent of the RNA synthesis decreased when the nuclei were were prepared from senescent cells. The decreased activity of RN