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Changes in WT1 splicing are associated with a specific gene expression profile in Wilms' tumour

✍ Scribed by Baudry, Dominique; Faussillon, Marine; Cabanis, Marie-Odile; Rigolet, Muriel; Zucker, Jean-Michel; Patte, Catherine; Sarnacki, Sabine; Boccon-Gibod, Liliane; Junien, Claudine; Jeanpierre, Cécile

Book ID
110066910
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
283 KB
Volume
21
Category
Article
ISSN
0950-9232

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Homozygous intragenic deletion in the WT1 gene in a sporadic Wilms' tumour associated with high levels of expression of a truncated transcript
✍ Elizabeth M. Algar; Mark T. Kenney; Lisa A. Simms; Shirley I. Smith; Yoshiki Kid 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 859 KB

Communicated by R. G. H. Cotton We have examined a panel of 21 sporadic Wilms' tumours for rearrangements in the Wilms' tumour suppressor gene, WT1. In one tumour with specific allele loss in chromosome llp13, a homozygous deletion in the 3' end of the gene, encompassing exon 10 and the 3' untransla