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Changes in the oral health of children during treatment for acute lymphoblastic leukaemia

✍ Scribed by ELIZABETH A. O'SULLIVAN; Dr. MONTY S. DUGGAL; C.C. BAILEY

Book ID
114731142
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
333 KB
Volume
4
Category
Article
ISSN
0960-7439

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Hepatotoxicity in the treatment of acute
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Serial liver function tests and percutaneous liver biopsies were performed on 21 children receiving treatment for acute lymphoblastic leukaemia (ALL). The patients received continuing chemotherapy either with daily 6-mercaptopurine and weekly methotrexate or with five-day pulses of these drugs every

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Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia
✍ P. Lafolie; S. Hayder; O. BjΓΆrk; C. Peterson πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 318 KB

Intraindividual variation in 6-mercaptopurine (6-MP) kinetics has been little studied. It has now been examined in 18 children with acute lymphoblastic leukaemia (ALL). On 2 to 4 occasions in each patient drug concentrations in plasma and red cells were followed for 4 h after administration by means