Changes in the ground substance of ageing cartilage
β Scribed by Loewi, G.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1953
- Tongue
- English
- Weight
- 404 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0368-3494
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π SIMILAR VOLUMES
## Abstract A study of the organization of proteoglycans in articular cartilage indicates that nonaggregated proteoglycans existed in larger numbers in osteoarthritic than in normal cartilage and that proteoglycan aggregates in arthritic cartilage were smaller than normal. After dissociation from h
Biochemical and biophysical studies have demonstrated that proteoglycan monomers from immature and adult articular cartilage differ in composition and size. To investigate the structural basis of age-related differences in articular cartilage proteoglycan monomers and aggregates, we isolated and pur