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Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats

✍ Scribed by Nancy Sarmiento; Carmen Sánchez-Bernal; Manuel Ayra; Nieves Pérez; Angel Hernández-Hernández; José J. Calvo; Jesús Sánchez-Yagüe


Book ID
116270634
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
721 KB
Volume
1782
Category
Article
ISSN
0925-4439

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The protein tyrosine phosphatase SHP-1 is predominantly expressed in hemopoietic cell lineages, where its function is relatively well defined. However, its expression profile also extends to certain epithelial cell types. Furthermore, the negative regulatory role of this enzyme in hemopoietic cell s