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Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

✍ Scribed by Kyung Hee Jung; Sang-Won Hong; Hong-Mei Zheng; Hee-Seung Lee; Hyunseung Lee; Don-Haeng Lee; Sang Yoon Lee; Soon-Sun Hong


Book ID
111264735
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
767 KB
Volume
48
Category
Article
ISSN
0742-3098

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## Abstract Adenosine, a purine nucleoside, has been reported to suppress the inflammatory responses of microglia in the brain. However, the underlying mechanisms of its anti‐inflammatory action are unclear at present. Here we show that adenosine reduces the increase in intracellular reactive oxyge