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Changes in the B-cell repertoire with age

โœ Scribed by Marc E Weksler


Book ID
117433780
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
99 KB
Volume
18
Category
Article
ISSN
0264-410X

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Objective. We sought to compare the frequencies of precursors producing IgM rheumatoid factors (IgM-RFs) in synovial fluid and peripheral blood B cells from patients with rheumatoid arthritis (RA). Methods. We used limiting-dilution analysis of Epstein-Barr virus-activated B cells from seropositive