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Changes in nuclear magnetic resonance (T2) relaxation of limb tissue with bed rest

✍ Scribed by Adrian Leblanc; Harlan Evans; Ernesto Schonfeld; Joseph Ford; Victor Schneider; Satish Jhingran; Philip Johnson

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
286 KB
Volume
4
Category
Article
ISSN
0740-3194

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✦ Synopsis

Bed rest is used to simulate the effects of weightlessness on human physiology. A spin-echo procedure was used to image the lower leg of 15 normal male volunteers before and after 5 weeks of horizontal bedrest. In addition to noninvasively measuring muscle size changes, accurate T2 images were produced to investigate possible relaxation time changes immediately (2-4 h) and 1-2 days after bed rest. Subcutaneous fat showed no change in T2, bone marrow showed a decrease, and muscle showed no change immediately after bed rest but increased 1-2 days following reambulation.

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