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Changes in glycolytic network and mitochondrial design in creatine kinase–deficient muscles

✍ Scribed by Ad J. C. de Groof; Frank T. J. J. Oerlemans; Carolina R. Jost; Bé Wieringa


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
282 KB
Volume
24
Category
Article
ISSN
0148-639X

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In skeletal muscle, creatine kinase imposes constraints on the concentrations of phosphocreatine, creatine, ATP and ADP, which complicate our understanding of the regulation of mitochondrial ATP synthesis, because correlations between oxidation rate \((Q)\) and metabolite concentrations cannot prove