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Changes in DNA methyltransferase induced by treatment with N-2-acetylaminofluorene

✍ Scribed by Luis M. Bravo; Carlos E. Salas

Book ID
113193723
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
430 KB
Volume
215
Category
Article
ISSN
0027-5107

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## Abstract In this study, the mutation frequencies of the p53 gene in rat hepatocellular carcinomas (HCCs) induced by __N__‐nitroso‐2‐acetylaminofluorene (NO‐AAF) and 2‐acetylaminofluorene (AAF) were 19.23% (20 of 104) and 31.1% (33 of 106), respectively. Four noteworthy features of the mutation s