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Changes in DNA alkali-sensitive sites during senescence and establishment of fibroblasts in vitro

โœ Scribed by R. Beaupain; C. Icard; A. Macieira-Coelho


Book ID
115747363
Publisher
Elsevier Science
Year
1980
Weight
518 KB
Volume
606
Category
Article
ISSN
0005-2787

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Poly(ADP-ribose) polymerase activity was determined at various times during the in vitro life span of two human diploid fibroblast-like cell lines of different donor ages. The cell lines differed in their ability to transfer ADP-ribose, with cells from an embryonic donor exhibiting 2 to 3 times the