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Change in nicotinic receptor subtypes in temporal cortex of Alzheimer brains

✍ Scribed by Nordberg, Agneta; Adem, Abdu; Hardy, John; Winblad, Bengt

Book ID
123524746
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
275 KB
Volume
86
Category
Article
ISSN
0304-3940

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Nicotinic acetylcholine receptor subtype
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## Abstract Molecular genetic and pharmacological studies have suggested that several subtypes of nicotinic acetylcholine receptors exist in the mammalian and avian brain. Combining ^3^H‐(βˆ’)‐nicotine, ^125^ I‐α‐bungarotoxin, and ^125^I‐κ‐bungarotoxin as ligands, we report here the first evidence fo