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Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases

✍ Scribed by Elaine Perry; Carmen Martin-Ruiz; Mandy Lee; Martin Griffiths; Mary Johnson; Margaret Piggott; Vahram Haroutunian; Joseph Daniel Buxbaum; Janne Nãsland; Kenneth Davis; Cecilia Gotti; Francesco Clementi; Socrates Tzartos; Onsat Cohen; Hermona Soreq; Evelyn Jaros; Robert Perry; Clive Ballard; Ian McKeith; Jennifer Court

Book ID
114012843
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
375 KB
Volume
393
Category
Article
ISSN
0014-2999

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Nicotinic acetylcholine receptor subtype
Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease
✍ K. Sugaya; E. Giacobini; V. A. Chiappinelli 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 993 KB

## Abstract Molecular genetic and pharmacological studies have suggested that several subtypes of nicotinic acetylcholine receptors exist in the mammalian and avian brain. Combining ^3^H‐(−)‐nicotine, ^125^ I‐α‐bungarotoxin, and ^125^I‐κ‐bungarotoxin as ligands, we report here the first evidence fo