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Cetirizine: A New Antihistamine with Minimal Sedation

โœ Scribed by Leslie Hendeles

Book ID
112113505
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
188 KB
Volume
16
Category
Article
ISSN
0277-0008

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โœ Joseph W. Polli; Todd M. Baughman; Joan E. Humphreys; Kelly H. Jordan; Angela L. ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 109 KB

Recent in vitro studies have suggested that P-glycoprotein (Pgp) and passive membrane permeability may influence the brain concentrations of non-sedating (second-generation) antihistamines. The purpose of this study was to determine the importance of Pgp-mediated efflux on the in vivo brain distribu