Efficient Williamson type O-alkylation of alcohols was developed using cesium bases in the presence of tetrabutylanmaonium iodide (TBAI) and molecular sieves. Various substrates including unreactive primary and secondary alcohols were converted smoothly to the corresponding ethers. Electrophiles use
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Cesium Hydroxide Promoted Chemoselective N-Alkylation for the Generally Efficient Synthesis of Secondary Amines
โ Scribed by Salvatore, Ralph N.; Nagle, Advait S.; Schmidt, Shaun E.; Jung, Kyung Woon
- Book ID
- 115491173
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 65 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1523-7060
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