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Cervical neurofibromas in children with NF-1

โœ Scribed by C. J. Chung; K. B. Armfield; Suresh K. Mukherji; Lynn A. Fordham; W. L. Krause


Book ID
105943044
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
252 KB
Volume
29
Category
Article
ISSN
0301-0449

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Neurofibromatosis 1 (NF1) is an autosomal dominant disorder caused by genetic alterations of the NF1 gene on 17q11.2. About 30% of NF1 patients develop plexiform neurofibromas (PNFs), which often cause severe clinical deficits. To determine whether there is a certain genotype underlying PNFs or subt