A case of a cutaneous squamous cell carcinoma (SCC) occurring at the site of a long-standing recurrent HSV infection is described. No deficit of the cell-mediated immunity was recorded. HSV2 was isolated in several viral cultures. HSV DNA was visualized in the SCC by in situ hybridization with bioti
Cervical carcinoma: Detection of herpes simplex virus RNA in cells undergoing neoplastic change
โ Scribed by James K. McDougall; Denise A. Galloway; Cecilia M. Fenoglio
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- French
- Weight
- 858 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
Abstract
^3^HโHSVโ2 DNA has been hybridized in situ to frozen sectioned tissue from human cervical biopsies. RNA complementary to the virusโspecific probe was detected in cells undergoing preโmalignant changes, but not in the cells of the fully developed squamousโcell cancer.
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