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Cerebrospinal fluid levels of amyloid β-protein in alzheimer's disease: Inverse correlation with severity of dementia and effect of apolipoprotein e genotype

✍ Scribed by Dr Roger M. Nitsch; G. William Rebeck; Meihua Deng; U. Ingrid Richardson; Marsha Tennis; Dale B. Schenk; Carmen Vigo-Pelfrey; Ivan Lieberburg; Richard J. Wurtman; Bradley T. Hyman; John H. Growdon


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
788 KB
Volume
37
Category
Article
ISSN
0364-5134

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## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin